Transgenesis & mouse genetics

Transgene expression in selected cell populations

 

Optogenetics, chemogenetics, & synaptic silencing

Interrogation and manipulation of cell/circuit activity

Deep learning motion tracking

Cell-specific interrogation of movement behavior

 

Viral-mediated genetic manipulations

Gene transfer and RNA interference

 

Anatomical circuit-mapping

Viral & conventional tracers mediated circuit architecture analysis

 

Ex vivo patch-clamp recording & fast-scan cyclic voltammetry

Examination of neurotransmission and cellular activity 

  

FACS-qPCR

Transcriptomic analyses from anatomically/genetically-identified cell population

 

Immunohistochemistry & in situ hybridization

Examination of transcript & protein expression in brain tissues

 

In vivo electrophysiology, imaging, & fiber-photometry

Examination of cellular & circuit activity in anesthetized or behaving mice

 

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